Zondag 1 november
| Hoogeveen | – | Nieuw Buinen | 2-1 |
| Germanicus | – | TEVV | 1-2 |
| Titan | – | ZNC | 0-3 |
| Dalen | – | Valthermond | 3-1 |
| Musselkanaal | – | SVV ‘04 | 2-0 |
| DVC ‘59 | – | Ter Apel ‘96 | 2-3 |
| Gieten | – | HODO | 5-2 |
| Zwartemeer | – | SC Stadskanaal | 2-2 |
| Eenrum | – | Alteveer | 1-1 |
| Pekelder Boys | – | Bellingwolde | 2-3 |
| Westerwolde | – | BATO | 4-1 |
| Bareveld | – | Sellingen | 3-1 |
| SPW | – | Oldambster Boys | 4-0 |
| Gasselternijveen | – | WEO | 0-4 |
| Veelerveen | – | JVV | 5-2 |
| HOC | – | Zandpol | 8-0 |
| SC Roswinkel | – | GKC | 4-5 |
| Buinerveen | – | DOS ‘63 | 2-3 |
| Eext | – | Buinen | 3-1 |
| EEC | – | Gieterveen | 0-2 |
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