Zondag 4 oktober
| Nieuw Buinen | – | Bergum | 1-1 |
| TEVV | – | Hoogezand | 3-1 |
| Titan | – | Dalen | 1-1 |
| Valthermond | – | Annen | 3-1 |
| Raptim | – | Gieten | 3-2 |
| Protos | – | Ter Apel ‘96 | 4-0 |
| Twedo | – | Musselkanaal | 1-1 |
| SC Stadskanaal | – | Zuidwolde | 0-0 |
| Haren | – | Westerwolde | 3-3 |
| Alteveer | – | Pekelder Boys | 3-1 |
| PJC | – | Gasselternijveen | 3-0 |
| JVV | – | Drieborg | 0-7 |
| Sellingen | – | DWZ | 3-1 |
| Veelerveen | – | SPW | 0-2 |
| Buinen | – | Zandpol | 4-2 |
| HHCombi | – | Buinerveen | 6-2 |
| GKC | – | HOC | 0-5 |
| Weiteveense Boys | – | EEC | 3-0 |
| Gieterveen | – | Eext | 4-2 |
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