Zondag 6 september
| Titan | – | Peize | 2-1 |
| Valthermond | – | Helpman | 3-1 |
| Zuidwolde | – | Gieten | 2-5 |
| Zwartemeer | – | Musselkanaal | 2-1 |
| SC Stadskanaal | – | DVC ‘59 | 3-0 |
| HODO | – | Ter Apel ’96 | 4-3 |
| Alteveer | – | Westerwolde | 3-1 |
| Pekelder Boys | – | Gruno | 0-1 |
| JVV | – | Gasselternijveen | 0-2 |
| Wedde | – | Sellingen | 1-0 |
| SPW | – | DWZ | 3-2 |
| DOS ‘63 | – | Buinen | 8-2 |
| Buinerveen | – | Eext | 2-5 |
| HHCombi | – | EEC | 0-1 |
| Weiteveense Boys | – | Gieterveen | 2-3 |
| GKC | – | Zandpol | 3-0 |
| VIOS O | – | HOC | 1-5 |
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