Uitslagen zondag 27 november
| Valthermond | – | Amicitia VMC | 4-1 |
| Titan | – | Gieten | 0-2 |
| Bargeres | – | Musselkanaal | 6-1 |
| SC Stadskanaal | – | Zwartemeer | 1-1 |
| Ter Apel ’96 | – | SVV ’04 | 1-0 |
| Engelbert | – | Alteveer | 0-5 |
| Gieterveen | – | Pekelder Boys | 3-1 |
| Zuidlaarderveen | – | Westerwolde | 0-4 |
| Schoonebeek | – | HOC | 1-5 |
| Sweel | – | Sellingen | 2-0 |
| Buinerveen | – | Zandpol | 2-5 |
| EEC | – | Valther Boys | 1-2 |
| Gasselternijveen | – | Weiteveense Boys | 0-8 |
| GKC | – | Buinen | 3-2 |
| SC Roswinkel | – | De Treffer ’16 | 8-1 |
| PJC | – | JVV | 6-0 |
| Nieuweschans | – | SPW | 1-3 |
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