Zondag 27 september
| Heerenveen | – | TEVV | 4-2 |
| Annen | – | Titan | 2-2 |
| Actief | – | Valthermond | 0-1 |
| Musselkanaal | – | HODO | 1-1 |
| Ter Apel ‘96 | – | SC Stadskanaal | 2-2 |
| Gieten | – | Zwartemeer | 3-1 |
| BATO | – | Alteveer | 2-5 |
| Meeden | – | Pekelder Boys | 2-1 |
| Westerwolde | – | HFC ‘15 | 1-1 |
| Sellingen | – | BNC | 3-1 |
| SPW | – | Drieborg | 5-0 |
| Gasselternijveen | – | Oldambster Boys | 3-1 |
| WEO | – | JVV | 9-0 |
| HOC | – | DOS ‘63 | 2-2 |
| EEC | – | GKC | 3-0 |
| Buinerveen | – | EHS ‘85 | 0-4 |
| Gieterveen | – | Buinen | 7-2 |
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