Uitslagen zondag 11 september
| Hoogeveen | – | Nieuw Buinen | 1-1 |
| GVAV-Rapiditas | – | Valthermond | 1-1 |
| SC Stadskanaal | – | Bargeres | 4-1 |
| Gieten | – | CEC | 1-4 |
| Twedo | – | Ter Apel ‘96 | 1-2 |
| Dalen | – | Musselkanaal | 2-0 |
| SVV ‘04 | – | Titan | 2-2 |
| Pekelder Boys | – | MOVV | 1-1 |
| Gieterveen | – | Bellingwolde | 2-0 |
| Alteveer | – | HSC | 4-0 |
| Westerwolde | – | Engelbert | 0-0 |
| Sellingen | – | EMMS | 0-8 |
| Zwartemeerse Boys | – | HOC | 0-3 |
| De Treffer ‘16 | – | Buinerveen | 2-1 |
| Buinen | – | VIOS O | 1-7 |
| GKC | – | WKE | 0-12 |
| Zandpol | – | Gasselternijveen | 4-1 |
| Weiteveense Boys | – | EEC | 1-0 |
| SPW | – | BNC | 6-1 |
| JVV | – | DWZ | 1-2 |
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